Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: A case report

Abstract

Background: To date, there is no standard treatment for unresectable malignant peritoneal mesothelioma; either best supportive care or systemic chemotherapy with palliative intent are accepted options. Case presentation: Here, we report the case of a 79-year old patient with malignant peritoneal mesothelioma who was treated with pemetrexed single-agent and obtained an impressive long-lasting response. Conclusion: Single-agent pemetrexed is a treatment option for malignant peritoneal mesothelioma in selected elderly patients or in patients with unpaired performance status. © 2006 Fasola et al; licensee BioMed Central Ltd.