Introduction to Protein Structure

Abstract

2nd ed. This new edition gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context, illustrated in colour to illuminate the structural principles described in the text. I. Basic Structural Principles -- 1. The Building Blocks -- 2. Motifs of Protein Structure -- 3. Alpha-Domain Structures -- 4. Alpha/Beta Structures -- 5. Beta Structures -- 6. Folding and Flexibility -- 7. DNA Structures -- II. Structure, Function and Engineering -- 8. DNA Recognition in Procaryotes by Helix-Turn-Helix Motifs -- 9. DNA Recognition by Eucaryotic Transcription Factors -- 10. Specific Transcription Factors Belong to a Few Families -- 11. An Example of Enzyme Catalysis: Serine Proteinases -- 12. Membrane Proteins -- 13. Signal Transduction -- 14. Fibrous Proteins -- 15. Recognition of Foreign Molecules by the Immune System -- 16. The Structure of Spherical Viruses -- 17. Prediction, Engineering and Design of Protein Structures -- 18. Determination of Protein Structures.