Risk factors and prevalence of helicobacter pylori infection in persistent high incidence area of gastric carcinoma in yangzhong city

73Citations
Citations of this article
146Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Aim. The aim of this study was to investigate the prevalence and risk factors of H. pylori infection in areas with high prevalence of gastric cancer in Jiangsu Province, China. Methods. A prospective epidemiologic survey of H. pylori infection was accomplished in a natural population of 5417 individuals in Yangzhong city. Questionnaires and 13C-urea breath test for H. pylori infection were performed. Results. Among 5417 subjects who completed questionnaires and 13C-urea breath test, 3435 (63.41%) were H. pylori positive. The prevalence reached a peak at the age of 30-39 years (90.82%). There was significant difference between sexes and women had a higher infection rate than men. The prevalence of H. pylori infection was also associated with eating kipper food and fried food. No association between H. pylori prevalence and smoking or drinking was found. Compared to healthy individuals, people with dyspeptic diseases (peptic ulcer, gastroenteritis) presented a high prevalence of H. pylori infection. Using multivariate logistic regression analysis, age and history of peptic ulcer and gastroenteritis were the independent predictors for H. pylori infection. Conclusions. Yangzhong city had a high prevalence of H. pylori infection and was related to several risk factors. The underlying mechanisms are needed to be further investigated. © 2014 Yangchun Zhu et al.

Cite

CITATION STYLE

APA

Zhu, Y., Zhou, X., Wu, J., Su, J., & Zhang, G. (2014). Risk factors and prevalence of helicobacter pylori infection in persistent high incidence area of gastric carcinoma in yangzhong city. Gastroenterology Research and Practice, 2014. https://doi.org/10.1155/2014/481365

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free