Spenolimycin, a new spectinomycin-type antibiotic iii. biological properties

Abstract

Spenolimycin is a new spectinomycin-type antibiotic isolated from Streptomyces gilvospiralis sp. nov. In vitro, it was active against a wide variety of aerobic Grampositive and Gram-negative bacteria and Neisseria gonorrhoeae. It was two to four-fold more active against TV. gonorrhoeae than spectinomycin. Spenolimycin was effective in the standard mouse protection test against Escherichia coli, Klebsiella pneumoniae and Streptococcus pneumoniae. © 1984, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.