The Effects of Ethanol Extract, Chayote (Sechium Edule (Jacq.) Swartz) Fraction and Juice on the High-density Lipoprotein Level in Male White Mice

Abstract

Background: Cholesterol imbalance occurs in Diabetes Mellitus, where high-density lipo-protein (HDL) levels are low and low-density lipoprotein (LDL) increases, where this imbalance results in the appearance of athero-sclerosis. HDL has antiarterosclerotic potential so it needs to be targeted for therapy. One of the bioactive compounds that have this effect is found in chayote (Sechium edule (Jacq.) Swartz). This study aimed to examine the effects of ethanol extract, Chayote (Sechium Edule (Jacq.) Swartz) fraction and juice on the HDL level in male white mice