Orthotopic xenograft model recapitulates the faithful organ-specific microenvironment and facilitates analyses involving tumor-stromal interactions that are crucial for developing new-generation cancer therapy. Herein, we describe the detailed rationales and protocols of a versatile orthotopic xenograft model for esophageal squamous cell carcinoma.
CITATION STYLE
Yu, V. Z., Ip, J. C. Y., Ko, J. M. Y., Tao, L., Lam, A. K., & Lung, M. L. (2020). Orthotopic Xenograft Mouse Model in Esophageal Squamous Cell Carcinoma. In Methods in Molecular Biology (Vol. 2129, pp. 149–160). Humana Press Inc. https://doi.org/10.1007/978-1-0716-0377-2_12
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