In this issue of Cancer Cell, Pei et al. and Kawauchi et al. describe murine models of an aggressive medulloblastoma subtype driven by Myc. These tumors have a cellular origin, microscopic appearance, and molecular profile distinct from those of three other major subgroups. Thus, the models fill a significant clinical need. © 2012 Elsevier Inc.
Eberhart, C. G. (2012, February 14). Three Down and One To Go: Modeling Medulloblastoma Subgroups. Cancer Cell. https://doi.org/10.1016/j.ccr.2012.01.013