The history of the development of DNA blotting is described in this chapter. DNA blotting, involving the transfer of electrophoretically separated DNA fragments to a membrane support through capillary action, is also known as Southern blotting. This procedure enables the detection of a specific DNA sequence by hybridization with probes. The term Southern blotting led to a "geographic" naming tradition, with RNA blotting bearing the name Northern blotting and protein transfer to membranes becoming known as Western blotting.
CITATION STYLE
Southern, E. (2015). The early days of blotting. In Western Blotting: Methods and Protocols (pp. 1–3). Springer New York. https://doi.org/10.1007/978-1-4939-2694-7_1
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