X-linked lymphoproliferative disease presenting as pancytopenia in a 10-month-old boy

Abstract

X-linked lymphoproliferative disease, also known as Duncan's syndrome, is a rare genetic disorder that causes exaggerated immune responses to Epstein-Barr virus (EBV) infection and often leads to death. Patient presentation varies but can include signs and symptoms typical of EBV, pancytopenia, and fulminant hepatitis. Copyright © 2010 S. N. Chadha and D. Amrol.