O papel da glutamina na terapia nutricional do transplante de medula óssea

Abstract

Glutamine is an ammo acid which is usually found in the skeletal muscles and it is conditionally essential where there is hyper cathabolism as in bone marrow transplantation. In these situations nutritional support therapy using L-GLN supplements is both safe and recommended, nere seems to be a use for amino acid with the goal of reducing the secondary effects, such as mucositis and digestive tract manifestations, of these transplants. There are data which suggest a prophylactic effect of the LGLN in relation to hepatic veno-occlusive disease in transplant patients. The utilisation of amino acid in combination with antioxidants either by enteral orparenteral means, are questions which should he answered through further study of selected and heterogeneous groups of hone marrow transplant patients.