Predicting CAR-T cell Immunotherapy Success through ImmunoPET

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Abstract

Chimeric antigen receptor (CAR)-T cell therapy has generated unprecedented advances in the treatment of hematologic cancers, but readily translatable imaging approaches to visualize the in vivo dynamics of CAR-T cells are lacking. Noninvasive PET imaging is the ideal tool to monitor CAR-T cells.

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Volpe, A., Nagle, V. L., Lewis, J. S., & Ponomarev, V. (2021). Predicting CAR-T cell Immunotherapy Success through ImmunoPET. Clinical Cancer Research, 27(4), 911–912. https://doi.org/10.1158/1078-0432.CCR-20-4297

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