Collagen–bioceramic smart composites

Abstract

Bone regeneration remains one of the most challenging issues of today. 3D scaffolds that mimic native bone have been widely used in many implantable prostheses and play a critical role in improving human health. Inspired by the composition of the natural bone, a variety of collagen-based composites reinforced with different resorbable bioceramics have been developed. To mimic the natural bone, some requirements are imposed on the collagen–bioceramic composites. This chapter focuses on collagen-based composites, starting with the main biomaterials used to obtain the composites, and the methods used for obtaining the collagen–bioceramics-type composites. Different practical aspects related to the processing and characterization of some collagen-based composites that mimic bone tissue are revealed. Also, some characteristics that proved their properties and smart composite– drug delivery systems of the collagen–bioceramic-type composites are discussed.