Acetaminophen (paracetamol, APAP) (> Figure 3.1) has been being used as an excellent an- algesic-antipyretic for a long time, and is included as an ingredient in many over-the-counter drugs of analgesics and cold drugs. However, when APAP is ingested in large amounts, it was reported to cause liver disorders [1]. For analysis of APAP, HPLC [2–18], LC/MS [19], LC/MS/MS [20], GC [21], GC/MS [22, 23] and capillary electrophoresis [24, 25] are being used. Among the methods, HPLC is most popular for its analysis. In this chapter, HPLC methods for analysis of APAP and its metabo- lites
CITATION STYLE
Bateman, D. N. (2016). Acetaminophen (Paracetamol). In Critical Care Toxicology (pp. 1–25). Springer International Publishing. https://doi.org/10.1007/978-3-319-20790-2_108-2
Mendeley helps you to discover research relevant for your work.