The development of animal models of HPV infection has given investigators a new set of tools to expand basic knowledge of the early events of infection in vivo. The use of HPV pseudovirions, in which the viral genome has been replaced with a reporter pseudogenome, in combination with advanced imaging techniques has facilitated and simplified studies using these models. Herein we provide details for a murine model of cervicovaginal HPV infection in conjunction with several methods for imaging and quantitating the transduced genes, both ex vivo and in vivo. © Springer Science+Business Media, LLC 2013.
CITATION STYLE
Kines, R. C., Kobayashi, H., Choyke, P. L., & Bernardo, M. L. (2013). Optical imaging of HPV infection in a murine model. Methods in Molecular Biology, 961, 141–150. https://doi.org/10.1007/978-1-62703-227-8_7
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