Overlap syndromes

Abstract

Systemic sclerosis (SSc) overlap syndrome is a term used to describe a very heterogeneous group of patients with features of different connective tissue diseases, combined with clinical signs of SSc. Up to now, no firm classification criteria for SSc overlap syndromes are established, but it is generally considered when musculoskeletal involvement or features of other rheumatic diseases are significantly greater than usually found in general SSc patients.