Deimination refers to the posttranslational conversion of protein-bound arginines into protein-bound citrullines, catalyzed by peptidyl arginine deiminase (PAD) enzymes (Vossenaar et al. 2003). Lack of a carrier tRNA for citrulline has established deimination as a posttranslational modification. Deimination and citrullination are interchangeably used for conversion of arginine into citrulline. To distinguish free arginine citrullination from protein-bound citrullination, we prefer referring to the latter as deimination (Bhattacharya 2009). Throughout this chapter we use deimination to refer to the conversion of protein-bound arginine modification into citrulline.
CITATION STYLE
Ding, D., Enriquez-Algeciras, M., Bonilha, V. L., & Bhattacharya, S. K. (2014). Deimination in ocular tissues: Present and future. In Protein Deimination in Human Health and Disease (pp. 295–303). Springer New York. https://doi.org/10.1007/978-1-4614-8317-5_16
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