PDZBase: A protein-protein interaction database for PDZ-domains

Abstract

Summary: PDZBase is a database that aims to contain all known PDZ-domain-mediated protein-protein interactions. Currently, PDZ-Base contains approximately 300 such interactions, which have been manually extracted from >200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through alignments (for the comparison of several interactions), or as residue-based diagrams including schematic secondary structure information (for individual complexes). © The Author 2004. Published by Oxford University Press. All rights reserved.