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The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated candidiasis

Journal of Infectious Diseases (2002) 185(10) 1483-1489
DOI: 10.1086/340511
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Abstract

Toll-like receptors (TLRs) represent the main class of pattern-recognition receptors involved in sensing pathogenic microorganisms. The aim of the present study was to assess the role of TLR4 in the defense against Candida albicans infection. The outgrowth of C. albicans was 10-fold higher in TLR4-defective C3H/HeJ mice, compared with that in control C3H/HeN mice (P

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Netea, M. G., Van der Graaf, C. A. A., Vonk, A. G., Verschueren, I., Van der Meet, J. W. M., & Kullberg, B. J. (2002). The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated candidiasis. Journal of Infectious Diseases, 185(10), 1483–1489. https://doi.org/10.1086/340511

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