The incidence of tumors with life-threatening effects has increased gradually over time; however, the mechanisms involved in tumor development have not been fully elucidated. Recent studies have shown that microRNA-7 (miR-7), which is endogenous non-coding RNA molecules of approximately 23 nucleotides, plays an important role in the occurrence and development of tumors as a key tumor suppressor. Mechanistic evidence showed that miR-7 is closely related to the growth, metastasis, and prognosis of various malignant tumors through regulating different target molecules, which suggest that miR-7 may be a new target for the clinical diagnosis and treatment of various tumors. In this review, we summarize current knowledge of the relationship between miR-7 and tumor development, diagnosis, and treatment.
CITATION STYLE
Zhao, J., Tao, Y., Zhou, Y., Qin, N., Chen, C., Tian, D., & Xu, L. (2015, October 29). MicroRNA-7: A promising new target in cancer therapy. Cancer Cell International. BioMed Central Ltd. https://doi.org/10.1186/s12935-015-0259-0
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