Intermittent clinical proteinuria and renal function in diabetes: Evolution and the effect of glycaemic control

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Abstract

The evolution of renal disease was studied in 12 insulin dependent diabetics selected for intermittent clinical proteinuria. After a run in period during which patients were studied three monthly for at least 12 months members of pairs of patients matched for age and duration of diabetes were allocated either to receive continuous subcutaneous insulin infusion or to continue with their usual conventional insulin injection therapy (controls) and studied three monthly for a further year. Mean (SEM) plasma glucose concentration and glycosylated haemoglobin (HbA1) value improved significantly in the insulin infusion group (glucose 10•1 (1.0) v 5•3 (0•3) mmol/1 (182 (18) v 95 (5) mg/100 ml);. © 1986, British Medical Journal Publishing Group. All rights reserved.

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Bending, J. J., Viberti, G. C., Keen, H., & Watkins, P. J. (1986). Intermittent clinical proteinuria and renal function in diabetes: Evolution and the effect of glycaemic control. British Medical Journal (Clinical Research Ed.), 292(6513), 83–86. https://doi.org/10.1136/bmj.292.6513.83

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