Abstract
Iodination of terminal alkynes using N-iodosuccinimide (NIS) in the presence of γ-Al2O3 was developed to afford 1-iodoalkynes with good to excellent yields (up to 99%). This described approach featured excellent chemoselectivity, good functional group tolerance, and utilization of an inexpensive catalyst.
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CITATION STYLE
APA
Yao, M., Zhang, J., Yang, S., Xiong, H., Li, L., Liu, E., & Shi, H. (2020). Efficient synthesis of 1-iodoalkynes: Via Al2O3 mediated reaction of terminal alkynes and N -iodosuccinimide. RSC Advances, 10(7), 3946–3950. https://doi.org/10.1039/d0ra00251h
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