Measurement of corpus callosum size using mri in nepalese population

Abstract

Corpus callosum (CC) is the main fiber tract connecting the cortical and sub-cortical regions of the right, left hemispheres, and plays an essential role in the integration of information between the two hemispheres. By using magnetic resonance imaging (MRI), the dimensions of corpus callosum can be studied. In this cross-sectional quantitative study 80 cases of normal MRI head were selected for study over two months. T1 weighted sagittal spin-echo images with slice thickness of 6 mm, planned from an axial and coronal image were used for measuring length and thickness of corpus callosum. Obtained data were analyzed using SPSS ver.20 software and shown in frequency, percentages and bar diagram. The mean Corpus callosum (CC) length was 68.06 mm in the study population (n=80). The mean thickness of Genu, Body and Splenium were 9.15,5.2 and 9.08 mm respectively and average thickness was 7.81 mm. Statistically significant differences in size of CC for various age groups in both sexes were observed. The mean length of CC was 68.06 mm and mean thickness of CC was 7.81 mm. There were variation in the size of CC with age and sex. The Pearson correlation Coefficient is 0.48829 between Age and Length of CC, its P-value is 0.0019.