Abstract
Structures of terpendoles A, B, C and D, novel acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors, were determined by spectroscopic studies. All terpendoles consist of diterpene and indole moieties in common. Terpendoles A, C and D possess an additional isoprenyl unit via oxygen atom(s) of their diterpene moieties. The relative stereochemistries of terpendoles C and D were confirmed by NOE experiments and X-ray crystallographic analysis. © 1995, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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CITATION STYLE
Nlshida, H., Tomoda, H., Tabata, N., Shiomi, K., Yang, D. J., Takayanagi, H., & ŌMura, S. (1995). Terpendoles, Novel ACAT Inhibitors Produced by Albophoma yamanashiensis II. Structure Elucidation of Terpendoles A, B, C and D. The Journal of Antibiotics, 48(1), 5–11. https://doi.org/10.7164/antibiotics.48.5
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