Pancreatoblastoma. Case report and review of literature

Abstract

Although pancreatoblastoma (PB) is a rare tumor, it is the most common malignant pancreatic tumor in children. Clin-ic presentation is insidious, so early diagnostic suspicion al-lows timely therapy. We reported 3 cases of PB treated at our center. The first two cases achieved complete disease response after full tumor resection. The first one is in complete remission at 7 months after chemotherapy. The second patient is in second complete remission at 206 months after diagnosis and 128 months after metastatic relapse. The third case died from disease progression 61 months after the initial metastatic unresectable tumor. Histology, clinical features and treatment options are discussed along with presentation of the cases.