Antiangiogenic metargidin peptide (AMEP) gene therapy in disseminated melanoma

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Abstract

Gene delivery by electroporation is an efficient method for transfecting genes into various tissues including tumors. Here we present the treatment protocol used in a phase 1 study on gene electrotransfer of plasmid DNA encoding an antiangiogenic peptide into cutaneous melanoma.

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Spanggaard, I., & Gehl, J. (2015). Antiangiogenic metargidin peptide (AMEP) gene therapy in disseminated melanoma. Methods in Molecular Biology, 1317, 359–364. https://doi.org/10.1007/978-1-4939-2727-2_20

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