Chemical Constituents from the Polar Fraction of Rubus suavissimus

Abstract

Systematic phytochemical study of the n -BuOH fraction of the aqueous extract of Rubus suavissimus resulted in the isolation of three diterpene glycosides namely rubusoside, suavioside-A and sugeroside; a phenolic glycoside quercetrin; and a lignan glycoside arctiin. The structures of the isolated compounds were characterized on the basis of extensive spectral data (1D and 2D NMR; and MS) and chemical studies which has not been reported earlier. This is the first report of the isolation of quercetrin and arctiin not only from the plant R. suavissimus but also from the genus Rubus . Also, herewith we are reporting the sweetness recognition threshold and sweetness enhancement effect of rubusoside, the major constituent of R. suavissimus .