The relationship between aberrant methylation and survival in non-small-cell lung cancers

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Abstract

The present study examined the relationship between methylation of five genes (p16INK4a, RASSF1A, APC, RARβ and CDH13) and patient survival in 351 cases of surgically resected lung cancers. While there was no relationship between the other genes and survival, p16INK4a methylation was significantly related to unfavourable prognosis in lung adenocarcinomas. © 2004 Cancer Research UK.

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Toyooka, S., Suzuki, M., Maruyama, R., Toyooka, K. O., Tsukuda, K., Fukuyama, Y., … Gazdar, A. F. (2004). The relationship between aberrant methylation and survival in non-small-cell lung cancers. British Journal of Cancer, 91(4), 771–774. https://doi.org/10.1038/sj.bjc.6602013

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