Abstract
A novel C-methylated biflavone, taiwanhomoflavone-B (1), together with known compounds, 7,4′,7″-tri-O-methylamentoflavone, 6-C-methylnaringenin and apigenin-7-O-beta-glucoside were isolated from an ethanolic extract of Cephalotaxus wilsoniana. The structure of 1 was elucidated on the basis of spectroscopic analysis. Taiwanhomoflavone-B is cytotoxic with ED50 values of 3.8 and 3.5 μg/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively. © 2002 Pharmaceutical Society of Japan.
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Kuo, Y. H., Hwang, S. Y., Kuo, L. M. Y., Lee, Y. L., Li, S. Y., & Shen, Y. C. (2002). A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana. Chemical and Pharmaceutical Bulletin, 50(12), 1607–1608. https://doi.org/10.1248/cpb.50.1607
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