Abstract
The effect of the carbimazole on expression of tumor necrosis factor (TNF-α) in liver, was investigated in an experimental model of high fat diet (HFD) induced obesity. The HFD (orally given for 4 months) induced TNF-α in liver tissue along with raised serum triglyceride (TG), cholesterol and high TSH (62%) In carbimazole (1 mg/100gbw) treatment, the induction of TNF-α was significantly inhibited, without affecting other parameters. It also improved the liver function, which was raised due to HFD in experimental control rats.
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Tripathi, Y. B., & Pandey, N. (2014). Carbimazole inhibits TNF-α expression in Fat-induced hypothyroidism. Journal of Diabetes and Metabolic Disorders, 13(1). https://doi.org/10.1186/s40200-014-0083-4
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