In this chapter we have focused on elementary interactions in tissue and tumor growth. In particular, CA models for contact inhibition and chemotactic interaction have been presented. Later we showed how different modeling modules can be combined in order to produce a model for the avascular tumor growth phase that can be analyzed in multicellular spheroids. The LGCA model is hybrid: it represents biological cells as discrete entities and molecular concentrations as continuous states.
CITATION STYLE
Tissue and tumor development. (2005). In Modeling and Simulation in Science, Engineering and Technology (Vol. 16, pp. 185–206). Springer Basel. https://doi.org/10.1007/0-8176-4415-6_10
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