Failure of Acute Digitalization to Influence Exercise Tolerance in Angina Pectoris

Abstract

A double-blind study was carried out in 15 anginal subjects without heart failure. Exercise was performed on a treadmill, and the onset of pain was timed twice before drug administration and one and two hours after intravenous placebo or digitalis. Effort tolerance, measured as the duration of exercise before appearance of angina, was not prolonged by the administration of lanatoside C beyond the limits of spontaneous variability. © 1966, British Medical Journal Publishing Group. All rights reserved.