Mouse models of vascular diseases

Abstract

This book is a methodological source on mice models of vascular diseases. Covering various areas, each chapter is written by a pioneering researcher who has developed an original vascular disease model. Notoriously difficult to reproduce, each model is described in detail and numerous photographs are provided with links to videos. Genetically modified mice are a very powerful tool for studying the pathogenesis of various diseases, including immunological and oncological disorders, but they had always been thought to be too small to be used in the field of cardiovascular disease. Recently, however, various mice models of vascular diseases have been reported, and these will make a substantial contribution to basic research on cardiovascular and metabolic disorders.