The Molecular and Cellular Mechanisms Responsible for the Anti-inflammatory and Immunosuppressive Effects of Glucocorticoids

  • Nocentini G
  • Migliorati G
  • Riccardi C
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Abstract

Glucocorticoids (GCs) are immunosuppressive agents that inhibit early and late manifestations of acute inflammation and modulate subsequent repair. Therefore, GCs are widely used to treat inflammatory conditions, allergies, and autoimmune diseases. GCs are also prescribed to prevent or treat acute and chronic transplant rejection and graft-versus-host disease.

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Nocentini, G., Migliorati, G., & Riccardi, C. (2015). The Molecular and Cellular Mechanisms Responsible for the Anti-inflammatory and Immunosuppressive Effects of Glucocorticoids. In Systemic Corticosteroids for Inflammatory Disorders in Pediatrics (pp. 25–41). Springer International Publishing. https://doi.org/10.1007/978-3-319-16056-6_4

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