The association between serum ß-hydroxybutyrate and milk fatty acid profile with special emphasis on conjugated linoleic acid in postpartum Holstein cows

Abstract

Background: Ketogenesis is a secondary metabolic pathway to provide energy to dairy cows during early lactation; however when the production of ketone bodies (acetoacetate, acetone, ß- hydroxybutyrate) is above certain levels a subclinical disorder may appear. The aim of the present study was to investigate the association between serum concentrations of ß- hydroxybutyrate (BHBA) and fatty acid (FA) profile of milk with emphasis in conjugated linoleic acid (CLA) in a population of early lactation Holstein cows. Fifty cows between parity 1 and 5, ranging from 14 to 21days in milk, were randomly selected from 3 farms of the central area of Chile for determination of serum BHBA concentrations, milk fat content, and milk FA profiles. Results: Cows were divided in low (n = 26) and high (n = 24) BHBA groups considering the median value of the serum concentration of BHBA (0.7mmol/L) (SEM = 0.094). Mean milk fat % was 3.45% and 3.60% for cows in the low and high BHBA groups, respectively (P = 0.15). Concentrations of several FA were significantly different between both groups. Specifically, mean CLA concentrations were 0.40% (4 ± 0.03g/kg) and 0.33% (3.3 ± 0.03g/kg) for the low and high BHBA groups, respectively (P = 0.05). Conclusions: It is concluded that early postpartum cows with serum BHBA > 0.7mmol/L tended to have higher milk fat % and had significantly lower concentrations of CLA than early postpartum cows with BHBA ≤ 0.7mmol/L.