Fear conditioning and extinction as a model of PTSD in mice

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Abstract

A primary symptom in the diagnosis of PTSD is the inability to control fear. Therefore, the study of fear and its inhibition are essential in understanding the disorder. This chapter will provide detailed protocols for fear conditioning and extinction which can be used as a model to further understand and study PTSD. Background, significance, and required materials will also be discussed. © 2011 Springer Science+Business Media, LLC.

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Gafford, G. M., & Ressler, K. J. (2011). Fear conditioning and extinction as a model of PTSD in mice. Neuromethods, 63, 171–184. https://doi.org/10.1007/978-1-61779-313-4_11

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