Nanosponge: New Colloidal Drug Delivery System for Topical Delivery

Abstract

Topical drug delivery system faced many problems like poor permeability, skin irritation, allergic reactions etc. The new developed colloidal system called nanosponge has potential to overcome these problems. Nanosponge are tiny sponges having size of about a virus and can easily penetrate through skin. Nanosponge play vital role in targeting drug delivery in a controlled manner. Both lipophilic and hydrophilic drugs are incorporated in nanosponge. The outer surface is typically porous, allowing controlled release of drug. They enhanced solubility, bioavailability reduce side effects and modify drug release. Nanosponge drug delivery system has emerged as one of the most promising fields in pharmaceutics. The objective of the review article is to discuss nanosponge with their method of preparation, evaluation and applications. © 2014 iGlobal Research and Publishing Foundation. All rights reserved.