Criticism of Baroreflex Estimation Methods in Time Domain

Abstract

This article analyzes the simplifications made by methods for assessing baroreflex sensitivity in the time domain, and also discuss the reason to apply them since by using other techniques, better results are achieved. The sequence method should be not applied without checking arterial blood pressure excursion. Using a linear model, as the majority of time-domain methods do, the error increases significantly when the pressure range increases. Additionally, with this novel approach, real curve points can be computed by grouping data, and consequently two important parameters like the setpoint and the gain peak can be obtained.