The replacement of retinal cells, or the support of surviving retinal neurons, in a degenerated retina presents a significant challenge in the fields of ophthalmology and regenerative medicine. Stem cell-based therapies are being explored as an approach for treating retinal dystrophies, such as retinitis pigmentosa (RP), Stargardt’s disease, and age-related macular degeneration (AMD). This review provides an update on the recent progress made toward the restoration of vision lost to degenerative disease using stem cell-based transplantation strategies and the challenges that need to be overcome. Both retinal pigmented epithelium (RPE) and photoreceptor replacement therapies are discussed.
CITATION STYLE
Cuevas, E., Parmar, P., & Sowden, J. C. (2019). Restoring Vision Using Stem Cells and Transplantation. In Advances in Experimental Medicine and Biology (Vol. 1185, pp. 563–567). Springer. https://doi.org/10.1007/978-3-030-27378-1_92
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