Loose Anagen Syndrome

Abstract

Loose anagen syndrome is a rare, benign condition that is self-limited. It involves anagen hairs being easily extractable without pain [1]. It is mainly seen in girls between 2 and 6 years old. LAS can be sporadic or inherited in an autosomal recessive pattern with variable expressivity. Usually children present with not requiring haircuts and hair not growing. Scalp hair is mainly involved, with rare involvement of eyebrow and other body hairs. The hair pull test and trichogram are diagnostic for the loose anagen syndrome. Physical exam may show sparse growth of hair with diffuse or patchy alopecia. The hair is very thin and fine in these patients. The occipital region is the most affected, presumably because of the friction of the head rubbing against the pillow at night, causing hair to be pulled out.