Beneficial Effect of Mesona palustris BL: A Review on Human and Animal Intervention

Abstract

BACKGROUND: Black Cincau (Mesona palustris BL) has been used widely as a complementary and alternative therapy in East and Southeast Asian regions due to its potent antioxidant activity and proven health benefits. It is traditionally used to treat various diseases such as antihypertensive, fever, and anti-diarrhea. Some studies to explore the function of Black Cincau were carried out on animal and humans, but publications regarding, it are still limited. AIM: This review emphasizes the beneficial effect of M. palustris BL. In addition, this review corroborates the pharmacological basis for the various health benefits, traditional, and medicinal applications of M. palustris BL. METHODS: All the available information of Black Cincau (M. palustris BL) was collected from electronic databases such as PubMed, Google Scholar, and ProQuest from 2011 to 2020. This literature review suggests that M. palustris BL has a beneficial effect. All Black Cincau (M. palustris BL) available information was collected from electronic databases such as PubMed, Google Scholar, and ProQuest from 2011 to 2020. RESULT: This literature review suggested that M. palustris BL has a beneficial effect. Researchers have proven in preclinical models that M. palustris BL is pharmacologically active as an antioxidant and can reduce cholesterol, blood glucose, immunomodulatory, and gastrointestinal healthy. CONCLUSION: Several preclinical studies on M. palustris BL have been carried out, but the application of the effectiveness of M. palustris BL in humans still needs to be developed to provide the pharmacological basis for the various health benefits, traditional, and medicinal applications of M. palustris BL.