Synthesis and Photophysical Characterization of Azoheteroarenes

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Abstract

A set of azoheteroarenes have been synthesized with Buchwald-Hartwig coupling and microwave-assisted O2 oxidation as the key steps. Several compounds exhibit good to excellent photoswitching properties (high switching efficiency, good fatigue resistance, and thermal stability of Z-isomer) relevant for photocontrolled applications, which pave the way for use in photopharmacology.

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Xu, Y., Gao, C., Andréasson, J., & Grøtli, M. (2018). Synthesis and Photophysical Characterization of Azoheteroarenes. Organic Letters, 20(16), 4875–4879. https://doi.org/10.1021/acs.orglett.8b02014

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