A review on the genetic regulation of myogenesis and muscle development

Abstract

Myogenesis of muscle tissues is known as a very complex and delicate process including many cellular differentiation and development events in animals. Here, the courses of cellular fate determination and terminal differentiation of muscle cells are systematically elaborated and the genetic regulatory network of muscle genesis is well conceived in animal organic growth and development through literature retrieval. Furthermore, the principal roles of myogenic regulatory factors, Myostatin, fibroblast growth factor, insulin-like growth factor and other muscular regulatory factors interrelated and reported in the myogenesis relevant studies are also reviewed. In addition, the interactions of these muscular specific factors and their possible relevant regulative pathways and interactions among them are included and developed too.