Effects of Soybean Trypsin Inhibitor on Hemostasis

  • A. E
  • E. I
  • A. M
  • et al.
N/ACitations
Citations of this article
19Readers
Mendeley users who have this article in their library.

Abstract

Soy bean trypsin inhibitor (SBTI) belongs to the family of serpins – serine protease inhibitors widely distributed in the nature [Silverman G.A. et al., 2004; 21]. Serpins participate in the regulation of proteopytic reactions underling very important physiological and pathological processes such as digestion [16], blood clotting [3, 14, 17], immunity [44] apoptosis [36, 42], inflammation [10], dystrophy [31], carcinogenesis [22, 11] and so on. Despite the apparent importance of the correction of imbalances of the proteolysis in pathology, in fact only the pancreatic trypsin inhibitor (aprotinin) is used more or less widely as a protease inhibitor drug (Trasisol, Contrical, Gordox etc) in the treatment of some diseases [24, 13, 40]. Being the animal protein aprotinin possesses substantial disadvantages [23, 12] and attempts to de‐ velop new drug on the base of plant or recombinant proteins or peptidomimetics are under‐ taken [35, 27]. SBTI is one of the candidates for such a role [34].

Cite

CITATION STYLE

APA

A., E., E., I., A., M., A., V., V., A., Tarumizu, C., … Yamamoto, S. (2013). Effects of Soybean Trypsin Inhibitor on Hemostasis. In Soybean - Bio-Active Compounds. InTech. https://doi.org/10.5772/52600

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free