Polymerized human placenta hemoglobin: Organ protective effects and alternative clinical uses

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Abstract

The inherent limitations of traditional blood transfusion have launched substantial efforts to develop blood substitutes, most of which are hemoglobin-based oxygen carriers (HBOCs). Polymerized human placenta hemoglobin (PolyPHb) is a promising HBOC developed in China. Based on its excellent oxygen transporting capacity, alternative uses of PolyPHb have been explored from several year ago. This review will summarize the results of animal studies about PolyPHb and discuss the potential alternative uses of PolyPHb in clinical situations.

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Li, T., Yang, C., Liu, J., Liu, J., & Hong, W. (2013). Polymerized human placenta hemoglobin: Organ protective effects and alternative clinical uses. In Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics (Vol. 9783642407178, pp. 399–410). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-40717-8_23

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