Macrophages are phagocytic cells that actively engulf and kill microorganisms within a specialized phagolysosomal system. Several pathogenic bacteria, however, actively co-opt host mechanisms and escape from microbial digestion to establish intracellular replication within macrophages. This chapter highlights detailed protocols to measure the effects of the LXR pathway on bacterial infection of murine bone marrow-derived macrophages.
CITATION STYLE
Glaría, E., Matalonga, J., & Valledor, A. F. (2019). Methods for assessing the effects of LXR agonists on macrophage bacterial infection. In Methods in Molecular Biology (Vol. 1951, pp. 135–141). Humana Press Inc. https://doi.org/10.1007/978-1-4939-9130-3_10
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