Homeostatic synaptic scaling is a form of synaptic plasticity that adjusts the strength of all of a neuron's excitatory synapses up or down to stabilize firing. Current evidence suggests that neurons detect changes in their own firing rates through a set of calcium-dependent sensors that then regulate receptor trafficking to increase or decrease the accumulation of glutamate receptors at synaptic sites. Additional mechanisms may allow local or network-wide changes in activity to be sensed through parallel pathways, generating a nested set of homeostatic mechanisms that operate over different temporal and spatial scales. © 2008 Elsevier Inc. All rights reserved.
CITATION STYLE
Marr, D., & Thach, W. T. (1991). A Theory of Cerebellar Cortex. In From the Retina to the Neocortex (pp. 11–50). Birkhäuser Boston. https://doi.org/10.1007/978-1-4684-6775-8_3
Mendeley helps you to discover research relevant for your work.