Abstract
A combined analytical procedure is presented for the quantification of experimentally induced Pt and Pd DNA adducts in living cells by combining a DNA extraction technique with double focusing magnet sector field ICP-MS instrumentation. The proposed method is discussed in terms of possible spectral interferences, instrumental repeatability and experimental reproducibility. The statistical evaluation of a large dataset indicates that the method can be successfully used in experimental studies for the quantification of Pt and Pd DNA adducts. © 2006 Springer-Verlag Berlin Heidelberg.
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Berner, Z., Menzel, C., Zeller, A., Eckhardt, J. D., Stüben, D., & Hartwig, A. (2006). Analytical procedure for the quantification of in vitro induced Pt- and Pd-DNA adducts in human lung cells. In Palladium Emissions in the Environment: Analytical Methods, Environmental Assessment and Health Effects (pp. 215–227). Springer Berlin Heidelberg. https://doi.org/10.1007/3-540-29220-9_16
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