Auto-Identification of Discrepancies between Urine Test Strip and Sediment Results Using Cross Check Function on Fully Automated Urine Analyzer

Abstract

Background: Urine chemistry (test strip/dipstick) and microscopy examination are the basic procedure of urinalysis. UX-2000 is the fully automated urine analyzer from Sysmex Corporation (Japan) which integrate urine test strip and urine particle assay on one platform. This instrument is also equipped with crosscheck function which can correlate the test strip and urine particle results and the flag for discrepancies. Aim: The aim of this study was to evaluate the crosscheck function of UX-2000 and to assess its impact on laboratory efficiency. Methods: 250 urine samples were collected and analyzed using UX-2000. Crosscheck results were obtained on 4 combination parameters: blood (BLD) & red blood cell (RBC), leukocyte esterase (LEU) & white blood cell (WBC), protein (PRO) & cast (CAST), and nitrite (NIT) & bacteria (BACT). Impact of crosscheck function on laboratory efficiency is determined using turn around time evaluation. Results: Crosscheck function results showed more than 85% concordance between urine test strip and urine sediment and raise flag for discrepancies. The application of this feature was able to reduce turnaround time from 7.5 into 5.4minutes. Conclusion: The crosscheck function of UX-2000 enabled more efficiency to identify discrepant results and reduce turnaround time urinalysis examination.