Antibacterial Activities of Crude Leaf and Bark Extracts of “Icheku” Dialium guineense on Bacterial Isolates from Bronchitis Patients

Abstract

The antibacterial activities of aqueous and ethanolic leaf and bark extracts of Dialium guineense were evaluated against clinical isolates of Klebsiella pneumoniae and Staphylococcus aureus using agar well diffusion technique. The photochemical analysis of Dialium guineense extracts were also carried out. The results showed that the extracts at varying concentrations, exerted antibacterial activities on the test organisms. The highest inhibition diameter (18 mm) at 0.8g/ml was recorded for cold water leaf extracts against Staphylococcus aureus and ethanol extracts inhibited the growth of the bacterial isolates in concentration dependent manner with minimum inhibitory concentration dependent manner with minimum inhibitory concentration (MIC) at 0.2 g/ml. The result of the physicochemical analysis showed the presence of flavonoids, alkaloids, tannin and saponin. These results suggest further exploitation of this material to possibly unveil its potential use for the treatment of diseases caused by the test organisms.