Adaptive fractional order sliding mode controller design for blood glucose regulation-4-3

Abstract

Diabetes is a growing health problem in worldwide. Especially, the patients with Type I diabetes need strict blood glucose level control because the body’s production and use of insulin are impaired, causing glucose concentration level to increase in the bloodstream. In this paper, fractional order sliding mode control and adaptive fractional order sliding mode control for robustly stabilize the glucose concentration level of a diabetic patient in presence of the parameter variations and multiple meal disturbance, is proposed. The Bergman minimal model is used to design the proposed controller. The structure of the proposed controllers is appropriate for making the insulin delivery pumps because attenuate the effect of chattering, obtain continuous control law and compliance with constraints insulin pump for subcutaneous injection of insulin. The numerical simulation result shows the advantages proposed controller for example robustness, high accuracy in presence of multiple disturbances with difference value and tracking of a desired glucose concentration in the appropriate time is verified.